Epitalon
Telomerase-stimulating tetrapeptide
Epitalon is a Khavinson tetrapeptide bioregulator (Ala-Glu-Asp-Gly / AEDG) modelled after the pineal-gland extract epithalamin in Russian gerontology research. It has been studied in animal and cell-culture models for telomerase activity, lifespan extension, and pineal-axis ageing parameters, and serves as the most widely cited member of the Khavinson short-peptide bioregulator panel alongside Pinealon, Cortagen, and the organ-targeted tetrapeptides. Sold by research-peptide vendors at 5–20 mg vial sizes for laboratory work; not approved by FDA, MHRA, Health Canada, or TGA for human use. Research-use only — Pepticker does not provide medical advice and this entry summarises published preclinical research, not a dosing protocol.
Also known as: Epithalamin, AEDG (Ala-Glu-Asp-Gly)
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Common questions about Epitalon
- What is Epitalon?
- Epitalon is a four-residue Khavinson short peptide (Ala-Glu-Asp-Gly / AEDG) modeled after the pineal-gland extract epithalamin. It has been studied in animal and cell-culture models for telomerase activity, lifespan extension, and pineal-axis ageing parameters.
- Is Epitalon FDA-approved?
- No. Epitalon is not approved by the FDA, MHRA, Health Canada, or the TGA for any human indication. Research-peptide vendors sell it for laboratory research only.
- What is the half-life of Epitalon?
- Published reports describe Epitalon as having a short circulating half-life on the order of minutes, while observed biological effects in cell-culture and animal models persist substantially longer than the plasma kinetics would suggest.
- What dose of Epitalon is used in research?
- Doses reported in published Russian gerontology and Khavinson-school studies vary by species, route, and endpoint. Pepticker does not publish a dosing protocol — refer to the original peer-reviewed studies you are reproducing.
- What is Epitalon commonly stacked with?
- Within the Khavinson short-peptide bioregulator panel, Epitalon is often discussed alongside Pinealon, Cortagen, and the organ-targeted tetrapeptides (Thymalin, Livagen, Cardiogen, etc.) in published Russian longevity research.
- Is Epitalon legal?
- Epitalon is sold for research use in the US, Canada, and the UK. In Australia it is TGA Schedule 4 and personal import is tightly controlled. Status is informational — not legal advice.
Editorial summary of published research. Not medical advice. See /methodology for sourcing.
Research use only. The compounds listed on this page are not approved for human use through research-chemical channels. Nothing on this page is medical advice. Consult a qualified clinician before considering any peptide protocol. See affiliate disclosure and our scoring methodology.