TB-500 is a synthetic fragment of the naturally-occurring thymosin beta-4 (Tβ4) peptide. It is studied in animal models for soft-tissue repair, actin sequestration, and inflammation modulation.

Is TB-500 FDA-approved?

No. TB-500 is not approved by the FDA or any major regulator for human use. It is sold by research-peptide vendors strictly for laboratory research.

What is the half-life of TB-500?

Rodent plasma studies report a half-life of roughly 1.5–3 hours, but tissue accumulation appears to prolong the functional effects beyond what circulating concentrations would predict.

What dose of TB-500 is used in research?

Published preclinical doses vary substantially by species, route, and endpoint. Pepticker does not publish a research dosing protocol — consult the original literature for the model you are reproducing.

Is TB-500 the same as Thymosin Beta-4?

No. TB-500 is a synthetic fragment of the full-length thymosin beta-4 molecule. Vendors selling 'TB-500' typically list this fragment; the parent compound is sold separately as Thymosin Beta-4 (TB-4).

What is TB-500 commonly stacked with?

Researchers most commonly pair TB-500 with BPC-157 in connective-tissue protocols and with GHK-Cu in skin and dermal-repair work, based on vendor and forum protocols.

healing

TB-500

Actin-binding healing fragment

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About

TB-500 is a synthetic fragment of the naturally-occurring thymosin beta-4 peptide, studied in animal models for soft-tissue repair and inflammation modulation.

Also known as: Thymosin Beta-4 fragment, TB500

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For research purposes only. Not for human consumption. Always verify calculations independently.

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§ Frequently asked

Common questions about TB-500

What is TB-500?: TB-500 is a synthetic fragment of the naturally-occurring thymosin beta-4 (Tβ4) peptide. It is studied in animal models for soft-tissue repair, actin sequestration, and inflammation modulation.
Is TB-500 FDA-approved?: No. TB-500 is not approved by the FDA or any major regulator for human use. It is sold by research-peptide vendors strictly for laboratory research.
What is the half-life of TB-500?: Rodent plasma studies report a half-life of roughly 1.5–3 hours, but tissue accumulation appears to prolong the functional effects beyond what circulating concentrations would predict.
What dose of TB-500 is used in research?: Published preclinical doses vary substantially by species, route, and endpoint. Pepticker does not publish a research dosing protocol — consult the original literature for the model you are reproducing.
Is TB-500 the same as Thymosin Beta-4?: No. TB-500 is a synthetic fragment of the full-length thymosin beta-4 molecule. Vendors selling 'TB-500' typically list this fragment; the parent compound is sold separately as Thymosin Beta-4 (TB-4).
What is TB-500 commonly stacked with?: Researchers most commonly pair TB-500 with BPC-157 in connective-tissue protocols and with GHK-Cu in skin and dermal-repair work, based on vendor and forum protocols.

Editorial summary of published research. Not medical advice. See /methodology for sourcing.

Research use only. The compounds listed on this page are not approved for human use through research-chemical channels. Nothing on this page is medical advice. Consult a qualified clinician before considering any peptide protocol. See affiliate disclosure and our scoring methodology.

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