healing

Thymosin Beta-4 (TB-4)

Full-length actin-sequestering peptide

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About

Full-length thymosin beta-4 — the parent molecule from which the TB-500 fragment is derived. Studied for cardiac repair, cornea healing, and hair growth.

Also known as: Tβ4, TMSB4

Commonly cited research dose ranges

Not medical advice. These are ranges reported in research literature, not personalized recommendations. Consult your physician.

Range42 – 1260 mg

Study type: Phase 1 dose-escalation safety studies in healthy volunteers evaluating intravenous synthetic thymosin beta-4.

Literature notes: Literature reports single and repeated intravenous dosing in phase 1 safety studies; subcutaneous routes were investigated in separate cohorts.

Citations

Goldstein et al., Ann N Y Acad Sci, 2010
“Synthetic thymosin beta-4 given intravenously over a dose range of 42–1260 mg was well tolerated with no evidence of dose-limiting toxicity.”
Wang et al., J Cell Mol Med, 2021
“Single and multiple subcutaneous doses of recombinant human thymosin β4 were safe and well tolerated in healthy volunteers.”

Last verified: May 3, 2026

Reconstitution calculator

For research purposes only. Not for human consumption. Always verify calculations independently.

VialPeptide mass in vial (mg)mgBacteriostatic water added (mL)mL

DoseDesired dose

Syringe

How reconstitution works · Understanding syringe units

Cost-per-dose recalculates as you adjust the calculator above.

Research use only. The compounds listed on this page are not approved for human use through research-chemical channels. Nothing on this page is medical advice. Consult a qualified clinician before considering any peptide protocol. See affiliate disclosure and our scoring methodology.

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