longevity
MOTS-c
Mitochondrial exerkine
Cheapest offer
$1.80/mg
23 vendors tracked30 live pricesLast crawl: 2026-06-09 12:03 UTC
About
A 16-residue peptide encoded within the mitochondrial 12S rRNA. Studied as an exercise-mimetic exerkine for metabolic health and longevity.
Also known as: Mitochondrial-derived peptide
Reconstitution calculator
!
For research purposes only. Not for human consumption. Always verify calculations independently.
Cost-per-dose recalculates as you adjust the calculator above.
MOTS-c · 10mg
22 vendors
B-
Operational$29.00
$2.90/mg· $14.50/dose
In stockOn sale
B
Operational$29.99
$3.00/mg· $14.99/dose
Out of stock▲ 3.4% vs best
Operational
$34.99
$3.50/mg· $17.50/dose
Out of stockOn sale▲ 20.7% vs best
B-
Operational$39.00
$3.90/mg· $19.50/dose
In stock▲ 34.5% vs best
Watch
$39.00
$3.90/mg· $19.50/dose
In stock▲ 34.5% vs best
B-
Operational$40.00
$4.00/mg· $20.00/dose
In stock▲ 37.9% vs best
B-
Operational$40.00
$4.00/mg· $20.00/dose
In stock▲ 37.9% vs best
Operational
$43.19
$4.32/mg· $21.59/dose
In stock▲ 48.9% vs best
Operational
$45.00
$4.50/mg· $22.50/dose
In stock▲ 55.2% vs best
B-
Watch$54.00
$5.40/mg· $27.00/dose
In stock▲ 86.2% vs best
B
Operational$54.00
$5.40/mg· $27.00/dose
In stock▲ 86.2% vs best
Operational
$54.99
$5.50/mg· $27.50/dose
In stock▲ 89.6% vs best
Operational
$57.99
$5.80/mg· $29.00/dose
In stock▲ 100.0% vs best
Watch
$59.99
$6.00/mg· $30.00/dose
In stock▲ 106.9% vs best
Operational
$61.75
$6.17/mg· $30.88/dose
In stock▲ 112.9% vs best
Watch
$64.99
$6.50/mg· $32.50/dose
In stock▲ 124.1% vs best
B-
Operational$69.00
$6.90/mg· $34.50/dose
In stock▲ 137.9% vs best
Operational
$89.99
$9.00/mg· $44.99/dose
In stock▲ 210.3% vs best
Operational
$109.97
$11.00/mg· $54.98/dose
In stock▲ 279.2% vs best
Operational
$116.00
$11.60/mg· $58.00/dose
In stock▲ 300.0% vs best
Operational
$119.99
$12.00/mg· $59.99/dose
In stockOn sale▲ 313.8% vs best
| Vendor | Grade | Risk | Price | $/mg | Trend | $/dose at 5 mg | Stock | |
|---|---|---|---|---|---|---|---|---|
| RetaOneLabs US | B- | Operational | $29.00 On sale | $2.90 | $14.50 | In stock | Buy with code → | |
| Welli Labs US | B | Operational | $29.99 ▲ 3.4% | $3.00 | $14.99 | Out | Visit → | |
| Double R Labs US | B | Operational | $34.99 On sale ▲ 20.7% | $3.50 | $17.50 | Out | Visit → | |
| Atomik Labz US | B- | Operational | $39.00 ▲ 34.5% | $3.90 | $19.50 | In stock | Visit → | |
| Solution Peptides US | B- | Watch | $39.00 ▲ 34.5% | $3.90 | $19.50 | In stock | Visit → | |
| Peptide Hub US | B- | Operational | $40.00 ▲ 37.9% | $4.00 | $20.00 | In stock | Visit → | |
| Purus Peptides US | B- | Operational | $40.00 ▲ 37.9% | $4.00 | $20.00 | In stock | Visit → | |
| Research Peptides Europe EU | A | Operational | $43.19 ▲ 48.9% | $4.32 | $21.59 | In stock | Visit → | |
| FITSKNS Research Group US | B- | Operational | $45.00 ▲ 55.2% | $4.50 | $22.50 | In stock | Visit → | |
| Peptira US | B | Operational | $49.00 ▲ 69.0% | $4.90 | $24.50 | In stock | Visit → | |
| Ameano Peptides US | B- | Watch | $54.00 ▲ 86.2% | $5.40 | $27.00 | In stock | Visit → | |
| EZ Peptides US | B | Operational | $54.00 ▲ 86.2% | $5.40 | $27.00 | In stock | Visit → | |
| One Day Compounds US | B- | Operational | $54.99 ▲ 89.6% | $5.50 | $27.50 | In stock | Visit → | |
| Research Peptides US | B | Operational | $57.99 ▲ 100.0% | $5.80 | $29.00 | In stock | Visit → | |
| Felix Chemical Supply US | B- | Watch | $59.99 ▲ 106.9% | $6.00 | $30.00 | In stock | Visit → | |
| Australian Peptides AU | B- | Operational | $61.75 ▲ 112.9% | $6.17 | $30.88 | In stock | Visit → | |
| Australian Peptide Store AU | B- | Watch | $64.99 ▲ 124.1% | $6.50 | $32.50 | In stock | Visit → | |
| Lab Sourced US | B- | Operational | $69.00 ▲ 137.9% | $6.90 | $34.50 | In stock | Visit → | |
| Ascension Peptides US | B | Operational | $89.99 ▲ 210.3% | $9.00 | $44.99 | In stock | Visit → | |
| BioLongevity Labs US | B | Operational | $109.97 ▲ 279.2% | $11.00 | $54.98 | In stock | Visit → | |
| Core Peptides US | A | Operational | $116.00 ▲ 300.0% | $11.60 | $58.00 | In stock | Visit → | |
| Nexus Peptides US | B | Operational | $119.99 On sale ▲ 313.8% | $12.00 | $59.99 | In stock | Visit → |
Sort:
Last crawl 2026-06-09Sort:
2026-06-09MOTS-c · 20mg
1 vendors
B
Operational$52.99
$2.65/mg· $13.25/dose
In stock◎ Best $/mg
| Vendor | Grade | Risk | Price | $/mg | Trend | $/dose at 5 mg | Stock | |
|---|---|---|---|---|---|---|---|---|
| Welli Labs US | B | Operational | $52.99 ◎ Best $/mg | $2.65 | $13.25 | In stock | Buy with code → |
Sort:
Last crawl 2026-06-09Sort:
2026-06-09MOTS-c · 40mg
7 vendors
B-
Operational$72.00
$1.80/mg· $9.00/dose
Out of stock◎ Best $/mg
Operational
$89.99
$2.25/mg· $11.25/dose
In stock▲ 25.0% vs best
B-
Operational$99.00
$2.48/mg· $12.38/dose
In stock▲ 37.5% vs best
Watch
$99.00
$2.48/mg· $12.38/dose
In stock▲ 37.5% vs best
Watch
$103.99
$2.60/mg· $13.00/dose
In stock▲ 44.4% vs best
B-
Operational$109.00
$2.73/mg· $13.63/dose
In stock▲ 51.4% vs best
| Vendor | Grade | Risk | Price | $/mg | Trend | $/dose at 5 mg | Stock | |
|---|---|---|---|---|---|---|---|---|
| RetaOneLabs US | B- | Operational | $72.00 ◎ Best $/mg | $1.80 | $9.00 | Out | Buy with code → | |
| AMC Essentials US | B | Operational | $89.99 ▲ 25.0% | $2.25 | $11.25 | In stock | Visit → | |
| Atomik Labz US | B- | Operational | $99.00 ▲ 37.5% | $2.48 | $12.38 | In stock | Visit → | |
| Solution Peptides US | B- | Watch | $99.00 ▲ 37.5% | $2.48 | $12.38 | In stock | Visit → | |
| Australian Peptide Store AU | B- | Watch | $103.99 ▲ 44.4% | $2.60 | $13.00 | In stock | Visit → | |
| Lab Sourced US | B- | Operational | $109.00 ▲ 51.4% | $2.73 | $13.63 | In stock | Visit → | |
| Peptira US | B | Operational | $139.00 ▲ 93.1% | $3.48 | $17.38 | In stock | Visit → |
Sort:
Last crawl 2026-06-09Sort:
2026-06-09§ Frequently asked
Common questions about MOTS-c
- What is MOTS-c?
- MOTS-c is a 16-residue peptide encoded within the mitochondrial 12S rRNA gene. It is studied as an exercise-mimetic exerkine for metabolic health, insulin sensitivity, and longevity-relevant endpoints in preclinical research.
- Is MOTS-c FDA-approved?
- No. MOTS-c is not approved for clinical use by the FDA, MHRA, Health Canada, or the TGA. Research-peptide vendors sell it for laboratory research only.
- What is the half-life of MOTS-c?
- Published rodent studies report a circulating half-life of roughly 1–2 hours, with exercise-induced peaks returning to baseline within about 4 hours after activity.
- What dose of MOTS-c is used in research?
- Doses reported in published preclinical studies vary substantially by species, route, and metabolic endpoint. Pepticker does not publish a dosing protocol — refer to the original study you are reproducing.
- Is MOTS-c the same as a GLP-1 agonist?
- No. MOTS-c is a mitochondrial-derived peptide that signals through pathways distinct from the GLP-1 axis. It is positioned in research as an exercise-mimetic rather than as a GLP-1-class metabolic compound.
- Is MOTS-c legal?
- MOTS-c is sold for research use in the US, Canada, and the UK. In Australia it is TGA Schedule 4 and personal import is tightly controlled. Status is informational — not legal advice.
Editorial summary of published research. Not medical advice. See /methodology for sourcing.
Research use only. The compounds listed on this page are not approved for human use through research-chemical channels. Nothing on this page is medical advice. Consult a qualified clinician before considering any peptide protocol. See affiliate disclosure and our scoring methodology.
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Guides & tools
- MOTS-c Mechanism and Dosing: The Mitochondrial Exercise-Mimetic Peptide
- How to reconstitute MOTS-c — visual step-by-step
- How to Reconstitute MOTS-c: Step-by-Step Visual Guide
- Reconstitution calculator
- Peptide stack builder
- Pepticker methodology
- How to read a peptide COA
- Research-use-only vs FDA-approved peptides
- How to read peptide prices per mg